| Museum of the Big Bend | Alpine | Brewster County | — | — | — |
 Arlington Museum of Art | Arlington | Tarrant County | 1989 | — | — |
| National Medal of Honor Museum | Arlington | Tarrant County | 2025 | — | 1717 East Randol Mill Road Suite 301 Arlington, TX 76011 |
 Bullock Texas State History Museum | Austin | Travis County | 2001 | — | — |
 Elisabet Ney MuseumNR | Austin | Travis County | 1911 | — | 304 E. 44th St. |
 George Washington Carver Museum and Cultural CenterNR | Austin | Travis County | 1980 | — | 1165 Angelina St. |
 Lyndon Baines Johnson Library and Museum | Austin | Travis County | 1971 | — | 2313 Red River Street, Austin, TX 78705 |
 Neill-Cochran HouseNR | Austin | Travis County | 1855 | — | 2310 San Gabriel St. Austin, TX 78705 |
 Southgate-Lewis HouseNR | Austin | Travis County | 1888 | — | 1501 E. 12th St. |
 Texas Military Forces Museum | Austin | Travis County | 1992 | — | — |
 The Contemporary Austin | Austin | Travis County | 1961 | — | — |
 The Thinkery | Austin | Travis County | 1983 | — | — |
 Babe Didrikson Zaharias Museum & Visitor Center | Beaumont | Jefferson County | — | — | — |
 Beaumont Children's Museum | Beaumont | Jefferson County | 2008 | — | — |
 Dishman Art Museum | Beaumont | Jefferson County | 1983 | — | — |
 Spindletop-Gladys City Boomtown Museum | Beaumont | Jefferson County | 1976 | — | — |
 Texas Energy Museum | Beaumont | Jefferson County | 1987 | — | — |
 Hangar 25 Air Museum | Big Spring | Howard County | — | — | — |
 Heritage Museum Big Spring | Big Spring | Howard County | — | — | 510 Scurry Street, Big Spring, Texas 79720 |
 Old McCulloch County JailNR | Brady | McCulloch County | — | — | 117 N. High St. |
 Brenham Heritage Museum | Brenham | Washington County | — | — | — |
 Brazos Valley Museum of Natural History | Bryan | Brazos County | 1961 | — | — |
 Buffalo Gap Historic Village | Buffalo Gap | Taylor County | — | — | — |
 Panhandle–Plains Historical Museum | Canyon | Randall County | 1933 | — | — |
 Texas Museum of Science and Technology | Cedar Park | Williamson County | 2015 | — | — |
| Chisholm Trail Outdoor Museum | Cleburne | Johnson County | — | — | — |
| Layland Museum | Cleburne | Johnson County | — | — | 201 North Caddo Street Cleburne, TX 76031 |
 George Bush Presidential Library | College Station | Brazos County | 1997 | — | 1000 George Bush Drive West |
 USS LexingtonNR | Corpus Christi | Nueces County | — | — | 2914 N. Shoreline Blvd. |
 Robert E. Howard Museum | Cross Plains | Callahan County | 1919 | — | — |
 African American Museum of Dallas | Dallas | Dallas County | 1974 | — | 3536 Grand Avenue, Dallas, Texas 75210 |
 Dallas County CourthouseNR | Dallas | Dallas County | 1892 | — | Houston and Commerce Sts. |
 Dallas Firefighter's Museum | Dallas | Dallas County | 1907 | — | — |
 Dallas Museum of Art | Dallas | Dallas County | 1903 | — | 1717 North Harwood Street |
 George W. Bush Presidential Center | Dallas | Dallas County | 2013 | — | 2943 SMU Boulevard |
 Museum of Earth History | Dallas | Dallas County | — | — | — |
 Museum of Geometric and MADI Art | Dallas | Dallas County | 2002 | — | — |
 Nasher Sculpture Center | Dallas | Dallas County | 1983 | — | 20001 Flora Street |
 Perot Museum of Nature and Science | Dallas | Dallas County | 2006 | — | — |
 The Ann and Gabriel Barbier-Mueller Museum | Dallas | Dallas County | 2012 | — | — |
| The Power Station | Dallas | Dallas County | 2011 | — | — |
 Frontiers of Flight Museum | Dallas Love Field | Dallas County | 1988 | — | — |
 Eisenhower Birthplace State Historic SiteNR | Denison | Grayson County | — | — | 720 South Lamar |
 El Paso Museum of Art | El Paso | El Paso County | 1959 | — | One Arts Festival Plaza |
 El Paso Museum of History | El Paso | El Paso County | 1974 | — | — |
 International Museum of Art | El Paso | El Paso County | — | — | — |
 National Border Patrol Museum | El Paso | El Paso County | 1985 | — | — |
 Amon Carter Museum of American Art | Fort Worth | Tarrant County | 1961 | — | — |
| Fort Worth Aviation Museum | Fort Worth | Tarrant County | — | — | — |
 Fort Worth Nature Center and Refuge | Fort Worth | Tarrant County | — | — | — |
 Kimbell Art Museum | Fort Worth | Tarrant County | 1972 | — | 3333 Camp Bowie Boulevard |
| Lenora Rolla Heritage Center Museum | Fort Worth | Tarrant County | 1979 | — | — |
 Modern Art Museum of Fort Worth | Fort Worth | Tarrant County | 1892 | — | 3200 Darnell Street |
 Sid Richardson Museum | Fort Worth | Tarrant County | 1982 | — | — |
| Cowboy Bronze Fine Art Gallery | Fredericksburg | Gillespie County | 2009 | — | — |
 National Museum of the Pacific War | Fredericksburg | Gillespie County | 1969 | — | — |
 Videogame History Museum | Frisco | Collin County | 2016 | — | — |
 Bryan Museum | Galveston | Galveston County | — | — | — |
 USS CavallaNR | Galveston | Galveston County | — | — | East End of Seawolf Park |
 USS StewartNR | Galveston | Galveston County | — | — | East End of Seawall Park |
 Barnard's MillNR | Glen Rose | Somervell County | — | — | 307 SW Barnard St. |
 Somervell County Historical Society Museum | Glen Rose | Somervell County | — | — | 101 Southwest Vernon Street |
 Audie Murphy American Cotton Museum | Greenville | Hunt County | 1987 | — | — |
 Deaf Smith County Historical MuseumNR | Hereford | Deaf Smith County | — | — | 508 W. 3rd Street Hereford, Texas |
 Bayou Bend Collection and GardensNR | Houston | Harris County | 1966 | — | 1 Westcott St. |
 Blaffer Art Museum | Houston | Harris County | 1973 | — | — |
 Byzantine Fresco Chapel | Houston | Harris County | — | closed 2011 | — |
 Caroline Wiess Law Building, Brown Pavilion | Houston | Harris County | — | — | 1001 Bissonnet Street, 77005 Houston |
| Caroline Wiess Law Building, Watkin Building | Houston | Harris County | — | — | 1001 Bissonnet Street, 77005 Houston |
 Contemporary Arts Museum Houston | Houston | Harris County | 1972 | — | — |
 Cullen Sculpture Garden | Houston | Harris County | 1986 | — | 1000 Bissonnet Street; Houston, TX 77005 |
 Houston Center for Contemporary Craft | Houston | Harris County | — | — | — |
 Lone Star Flight Museum | Houston | Harris County | 1985 | — | — |
 Menil Collection | Houston | Harris County | 1987 | — | — |
| Museum of Fine Arts, Cullinan Hall and Brown Pavilion | Houston | Harris County | — | — | 1001 Bissonnet Street, 77005 Houston |
 Museum of Fine Arts, Houston | Houston | Harris County | 1900 | — | 5100 Montrose Boulevard |
 National Museum of Funeral History | Houston | Harris County | 1992 | — | — |
 Rothko ChapelNR | Houston | Harris County | 1971 | — | 1409 Sul Ross Ave. |
 Space Center Houston | Houston | Harris County | 1992 | — | 1601 NASA Parkway, Houston, Texas 77058 |
 The Health Museum | Houston | Harris County | 1969 | — | — |
 Sam Houston Memorial Museum | Huntsville | Walker County | — | — | — |
 Sam Houston State Natural History Collections | Huntsville | Walker County | 2019 | — | 710 University Avenue Huntsville, Texas 77320 |
| Anne Dean Turk Fine Arts Center | Kilgore | Gregg County | 1966 | — | — |
| Texas Museum of Broadcasting and Communications | Kilgore | Gregg County | 2016 | — | 416 E Main St, Kilgore, TX 75662 |
| Longview Museum of Fine Arts | Longview | Gregg County | — | — | — |
 Buddy Holly Center | Lubbock | Lubbock County | 1999 | — | — |
 Museum at Texas Tech University | Lubbock | Lubbock County | 1929 | — | — |
| Naranjo Museum of Natural History | Lufkin | Angelina County | — | — | — |
 Chinati Foundation | Marfa | Presidio County | 1986 | — | Cavalry Row 1 |
| Presidential Museum and Leadership Library | Odessa | Ector County | 1965 | — | — |
 White-Pool HouseNR | Odessa | Ector County | — | — | 112 E. Murphy St. |
| Crockett County Museum | Ozona | Crockett County | 1939 | — | — |
 Museum for East Texas Culture | Palestine | Anderson County | 1982 | — | — |
 Carson County Square House MuseumNR | Panhandle | Carson County | 1967 | — | 5th and Elsie Sts. |
 Lamar County Historical Museum | Paris | Lamar County | — | — | — |
 Southfork Ranch | Parker | Collin County | — | — | — |
 Northeast Texas Rural Heritage Center and Museum | Pittsburg | Camp County | — | — | 204 W. Marshall, Pittsburg, Texas 75686 |
| National Roller Coaster Museum and Archives | Plainview | Hale County | 2009 | — | — |
| Museum of the Gulf Coast | Port Arthur | Jefferson County | 1964 | — | — |
 Garza County Historical Museum | Post | Garza County | — | — | — |
 Central Texas Museum of Automotive History | Rosanky | Bastrop County | 1980 | closed 2012 | — |
| Holocaust Memorial Museum of San Antonio | San Antonio | Bexar County | — | — | — |
 McNay Art Museum | San Antonio | Bexar County | 1954 | — | — |
| Museum of Aerospace Medicine | San Antonio | Bexar County | — | — | — |
 O. Henry House Museum | San Antonio | Bexar County | 1999 | — | — |
 Ruby City | San Antonio | Bexar County | — | — | 150 Camp Street, San Antonio, TX 78204 |
 Sala Diaz | San Antonio | Bexar County | 1995 | — | 517 Stieren, San Antonio, TX 78210 |
 San Antonio Museum of Art | San Antonio | Bexar County | 1981 | — | 200 West Jones Avenue |
 Dick's Classic Garage | San Marcos | Hays County | 1980 | — | — |
 Stanzel model aircraft museum | Schulenburg | Fayette County | — | — | 311 Baumgarten St, Schulenburg, TX 78956, United States |
 Stonewall Saloon (Saint Jo, Texas) | St. Jo | Montague County | 1873 | — | 100 Main Street |
 Hopkins County Museum and Heritage Park | Sulphur Springs | Hopkins County | — | — | 416 North Jackson Street, Sulphur Springs, Texas 75482 |
 Temple Railroad and Heritage Museum | Temple | Bell County | — | — | — |
 Ace of Clubs HouseNR | Texarkana | Bowie County | 1988 | — | 420 Pine Street |
 Museum of Regional HistoryNR | Texarkana | Bowie County | 1971 | — | 219 State Line Avenue |
 Discovery Science Place | Tyler | Smith County | — | — | — |
| Cynthia Woods Mitchell Center for the Arts | University of Houston | Harris County | 2003 | — | — |
| Texas Fashion Collection | University of North Texas | Denton County | 1938 | — | — |
 Red Men Museum and Library | Waco | McLennan County | 1991 | — | — |
| National Vietnam War Museum | Weatherford | Parker County | — | — | — |
 Professional Wrestling Hall of Fame and Museum | Wichita Falls | Wichita County | 2002 | — | — |
| Wichita Falls Museum of Art | Wichita Falls | Wichita County | — | — | — |